ChemicalBook CAS DataBase List Bromodiphenylmethane

Bromodiphenylmethane synthesis

13synthesis methods

Product Name:Bromodiphenylmethane
CAS Number:776-74-9
Molecular formula:C13H11Br
Molecular Weight:247.13

91-01-0 Synthesis

91-01-0
501 suppliers
$6.00/10g

631-61-8 Synthesis

631-61-8
761 suppliers
$11.19/100G

954-67-6 Synthesis

954-67-6
3 suppliers
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776-74-9
242 suppliers
$26.57/25g

Yield:954-67-6 71% ，776-74-9 17%

Reaction Conditions:

with N-Bromosuccinimide;triphenylphosphine in acetonitrile at 20; for 14 h;Cooling with ice;

Steps:

Typical procedure for the conversion of 3-phenylpropanol into 3-phenylpropyl acetate using Ph3P/Br2/NH4OAc

General procedure: To a solution of Ph3P(OAc)2, was added 3-phenylpropanol (1 mmol, 0.137 mL). The progress of the reaction was monitored by TLC (Table 3, entry 2). After completion of the reaction (0.3 h) the reaction mixture was filtered to remove the precipitated NH4Br followed by evaporation of the solvent. Column chromatography of the crude mixture on silica gel using n-hexane/EtOAc (3:1) as the eluent gave 3-phenylpropyl acetate in 90% yield (0.159 g).

References:

Iranpoor, Nasser;Firouzabadi, Habib;Elham, Etemadi Davan [Tetrahedron Letters,2013,vol. 54,# 14,p. 1813 - 1816]