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ChemicalBook CAS DataBase List (R)-3-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID

(R)-3-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID synthesis

11synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: ammonium formate / ethanol / 4 h / Reflux
2: phenylalanine ammonia lyase from Streptomyces maritimus; phenylalanine ammonia α-lyase from Anabaena variabilis / aq. buffer / 24 h / 30 °C / pH 8 / Resolution of racemate; Enzymatic reaction

References:

Weise, Nicholas J.;Ahmed, Syed T.;Parmeggiani, Fabio;Turner, Nicholas J. [Advanced Synthesis and Catalysis,2017,vol. 359,# 9,p. 1570 - 1576]

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