ChemicalBook CAS DataBase List Thiodiglycolic acid

Thiodiglycolic acid synthesis

11synthesis methods

Product Name:Thiodiglycolic acid
CAS Number:123-93-3
Molecular formula:C4H6O4S
Molecular Weight:150.15

63-68-3 Synthesis

63-68-3
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$5.00/25g

79-11-8
10 suppliers
$24.00/25g

2444-37-3 Synthesis

2444-37-3
79 suppliers
$7.00/250mg

123-93-3
272 suppliers
$8.00/25g

2185-03-7 Synthesis

2185-03-7
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$5.00/100mg

Yield:-

Reaction Conditions:

in water at 80; for 8 h;Overall yield = 162.1 g;

Steps:

5.1 (1) Preparation of compounds IV, V, VI:
To a 1 L four-necked flask, 90 g (0.6 mol) of L-methionine, 79.4 g (0.84 mol) of chloroacetic acid, and 500 ml of water were added, and the mixture was stirred uniformly, and slowly heated to 80 ° C to carry out a reaction for 8 hours; After the reaction is over, recovering solvent water under reduced pressure and reduced pressure, a total of 162.1 g of a mixture of L-homoserine lactone hydrochloride, (methylthio)acetic acid and thiodiacetic acid was obtained, and the next step reaction was carried out without isolation;

References:

Shandong Nong Pharmaceutical Xue Institute;Xie Yinping;Chai Hongwei;Dong Wenkai;Han Jintao;Cong Yunbo;Wang Xiuli;Zhang Zuoshan;Li Xukun CN108774160, 2018, A Location in patent:Paragraph 0076; 0078

FullText

79-11-8
10 suppliers
$24.00/25g

123-93-3
272 suppliers
$8.00/25g

References

348-67-4 Synthesis