ChemicalBook--->CAS DataBase List--->1000010-33-2

1000010-33-2

Request For Quotation
1000010-33-2 Structure

1000010-33-2 Structure
IdentificationBack Directory
[Name]

1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)-
[CAS]

1000010-33-2
[Synonyms]

AQXMN115
AQX-MN115
AQX MN115
1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)-
[Molecular Formula]

C21H30O2
[MOL File]

1000010-33-2.mol
[Molecular Weight]

314.46
Chemical PropertiesBack Directory
[Boiling point ]

440.3±25.0 °C(Predicted)
[density ]

1.094±0.06 g/cm3(Predicted)
[pka]

9.94±0.70(Predicted)
Hazard InformationBack Directory
[Description]

AQX-MN115 is a SH2-?containing inositol 5-?phosphatase (SHIP 1) modulator.
[Uses]

SHIP1 activator 1 is an SH3 domain-containing inositol 5-phosphatase regulator with SHIP1 activating activity. SHIP1 activator 1 retains its SHIA-1 activating ability by removing unnecessary functional groups. SHIP1 activator 1 is able to activate SHIP1 in vitro, inhibit Akt phosphorylation in MOLT-4 cells, and show dose-dependent activity in a mouse model of inflammation. SHIP1 activator 1 is an important chemical tool for evaluating the potential of SHIP1 activators as inhibitors of hematopoietic diseases involving abnormal PI3K cell signaling[1].
[References]

[1] Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol
1000010-33-2 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.  
Telephone: +86-057181025280; +8617767106207
Website: https://www.molcore.com/
Tags:1000010-33-2 Related Product Information
12141-67-2