| Identification | Back Directory | [Name]
Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide, (9α,13α,14α)- | [CAS]
1000026-77-6 | [Synonyms]
Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide, (9α,13α,14α)- | [Molecular Formula]
C19H23NO5 | [MOL File]
1000026-77-6.mol | [Molecular Weight]
345.4 |
| Hazard Information | Back Directory | [Description]
Sinomenine N-oxide is a plant extract with anti-angiogenic, anti-inflammatory and anti-rheumatic properties. It is also an inhibitor of NO production with an IC50 value of 23.04 μM.
| [Uses]
Sinomenine N-oxide has anti-angiogenic, anti-inflammatory and anti-rheumatic effects. Sinomenine N-oxide is also a NO production inhibitor, with an IC50 value of 23.04 μM[1][2][3]. | [References]
[1] Liu WJ, et al. Network pharmacology approach to elucidate possible action mechanisms of Sinomenii Caulis for treating osteoporosis. J Ethnopharmacol. 2020 Jul 15;257:112871. DOI:10.1016/j.jep.2020.112871
[2] Zeng HL, et al. New N-oxide alkaloids from the stems of Sinomenium acutum. Fitoterapia. 2023 Mar;165:105404. DOI:10.1016/j.fitote.2022.105404
[3] Li Q, et al. Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide. Life Sci. 2020 Nov 15;261:118433. DOI:10.1016/j.lfs.2020.118433 |
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Henan Alfachem Co.,Ltd.
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0371-55051623 18137891487 |
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www.chemicalbook.com/supplier/14555231/ |
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cjbscvictory
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13348960310 |
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https://www.weikeqi-biotech.com/ |
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