1000392-25-5

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1000392-25-5 Structure

Identification	Back Directory
[Name] Histamine H3 antagonist-1
[CAS] 1000392-25-5
[Synonyms] Histamine H3 antagonist-1
[Molecular Formula] C24H28F3N3O2
[MOL File] 1000392-25-5.mol
[Molecular Weight] 447.49

Chemical Properties	Back Directory
[Boiling point ] 528.1±50.0 °C(predicted)
[density ] 1.257±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 9.42±0.20(predicted)

Hazard Information	Back Directory
[Uses] Histamine H3 antagonist-1 (Compound 10o) is a histamine H3 antagonist and a serotonin reuptake inhibitor, which can be used in depression research[1].
[References] [1] Ly KS, et al. Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors. Bioorg Med Chem Lett. 2008;18(1):39-43. DOI:10.1016/j.bmcl.2007.11.016

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