ChemicalBook--->CAS DataBase List--->10024-89-2

10024-89-2

10024-89-2 Structure

10024-89-2 Structure
IdentificationBack Directory
[Name]

MORPHOLINIUM CHLORIDE
[CAS]

10024-89-2
[Synonyms]

Morpholine HCl
MORPHOLINIUM CHLORIDE
Morpholinhydrochlorid
Morphol Hydrochloride
Morpholin hydrochloride
MORPHOLINE HYDROCHLORIDE
Morpholinium hydrochloride
Morpholine, hydrochloride (1:1)
MORPHOLINIUM CHLORIDE FOR SYNTHESIS
[EINECS(EC#)]

233-029-4
[Molecular Formula]

C4H10ClNO
[MDL Number]

MFCD00035287
[MOL File]

10024-89-2.mol
[Molecular Weight]

123.58
Chemical PropertiesBack Directory
[Melting point ]

204℃
[storage temp. ]

Store below +30°C.
[Water Solubility ]

Soluble in water
[form ]

powder to crystal
[color ]

White to Light yellow
[InChI]

InChI=1S/C4H9NO.ClH/c1-3-6-4-2-5-1;/h5H,1-4H2;1H
[InChIKey]

JXYZHMPRERWTPM-UHFFFAOYSA-N
[SMILES]

C1NCCOC1.Cl
[CAS DataBase Reference]

10024-89-2
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
[Toxicity]

mouse,LD50,intraperitoneal,1350mg/kg (1350mg/kg),BEHAVIORAL: ANTIPSYCHOTICLUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION,Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967.
Hazard InformationBack Directory
[Chemical Properties]

White Crysstalline
[Uses]

MORPHOLINIUM CHLORIDE is used as a pharmaceutical intermediate for morpholine guanidine.
[Synthesis]

Morpholine

110-91-8

MORPHOLINIUM CHLORIDE

10024-89-2

GENERAL PROCEDURE: Ammonium chloride (0.54 g, 10 mmol) and ethanol (3 mL) were added to a 25 mL round bottom flask, followed by morpholine (10 mmol). The reaction mixture was placed on a magnetic stirrer and heated to reflux for 2 hours. After completion of the reaction, the solvent was removed by rotary evaporator to give morpholine hydrochloride as a white solid in quantitative yield.

[References]

[1] Synthetic Communications, 2015, vol. 45, # 22, p. 2601 - 2607
[2] Main Group Metal Chemistry, 2016, vol. 39, # 5-6, p. 175 - 181
[3] Patent: WO2008/95943, 2008, A1. Location in patent: Page/Page column 50; 122-123
[4] Advanced Synthesis and Catalysis, 2010, vol. 352, # 7, p. 1135 - 1136
[5] Patent: US2010/204235, 2010, A1. Location in patent: Page/Page column 5; 27; 28
Spectrum DetailBack Directory
[Spectrum Detail]

MORPHOLINIUM CHLORIDE(10024-89-2)1HNMR
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