| Identification | Back Directory | [Name]
6-HYDROXY-2-METHYLAMINOPURINE | [CAS]
10030-78-1 | [Synonyms]
N2-METHYLGUANINE
6-HYDROXY-2-METHYLAMINOPURINE
2-(MethylaMino)-7H-purin-6-ol
2-(MethylaMino)-1H-purin-6(7H)-one
2-methylamino-3,7-dihydropurin-6-one
1,7-Dihydro-2-(methylamino)-6H-purin-6-one
2-(methylamino)-6,7-dihydro-3H-purin-6-one
6H-Purin-6-one,1,9-dihydro-2-(methylamino)-
Endogenous Metabolite,Inhibitor,Bacterial,2 (Methylamino) 1H purin 6(7H) one,2(Methylamino)1Hpurin6(7H)one,inhibit,DNA/RNA Synthesis | [Molecular Formula]
C6H7N5O | [MDL Number]
MFCD00127896 | [MOL File]
10030-78-1.mol | [Molecular Weight]
165.15 |
| Chemical Properties | Back Directory | [Melting point ]
>300 °C (decomp) | [density ]
1.79±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, Inert atmosphere | [solubility ]
DMSO : < 1 mg/mL (insoluble or slightly soluble) | [form ]
Solid | [pka]
9.86±0.20(Predicted) | [color ]
Light yellow to khaki |
| Hazard Information | Back Directory | [Uses]
2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids. | [Definition]
ChEBI: N(2)-methylguanine is a methylguanine in which the methyl group is located at the N2-position. It has a role as a human metabolite. It is a methylguanine and a secondary amino compound. | [IC 50]
Human Endogenous Metabolite | [References]
[1] Rife JP, et al. N 2-methylguanosine is iso-energetic with guanosine in RNA duplexes and GNRA tetraloops. Nucleic Acids Res. 1998 Aug 15;26(16):3640-4. DOI:10.1093/nar/26.16.3640
[2] Youvan DC, et al. Reverse transcriptase pauses at N2-methylguanine during in vitro transcription of Escherichia coli 16S ribosomal RNA. Proc Natl Acad Sci U S A. 1979 Aug;76(8):3751-4. DOI:10.1073/pnas.76.8.3751 |
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NovoChemy Ltd.
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www.novochemy.com |
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Rhawn Reagent
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