ChemicalBook--->CAS DataBase List--->1006711-90-5

1006711-90-5

1006711-90-5 Structure

1006711-90-5 Structure
IdentificationBack Directory
[Name]

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-2-oxoethyl]-
[CAS]

1006711-90-5
[Synonyms]

DOTA-Maleimide
Maleimido-mono-amide-DOTA,DOTA-Maleimide
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-2-oxoethyl]-
[Molecular Formula]

C22H34N6O9
[MOL File]

1006711-90-5.mol
[Molecular Weight]

526.54
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to yellow
[InChIKey]

AUTDIWAXETZSGJ-UHFFFAOYSA-N
[SMILES]

N1(CC(O)=O)CCN(CC(NCCN2C(=O)C=CC2=O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
Hazard InformationBack Directory
[Uses]

Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
[Biological Activity]

Maleimide-DOTA is a non-degradable ADC linker for antibody drug conjugate (ADC) synthesis.
[target]

Non-cleavable

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[IC 50]

Non-cleavable Linker
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