| Identification | Back Directory | [Name]
GSK1521498 | [CAS]
1007573-18-3 | [Synonyms]
GSK1521498
GSK1521498 free base
GSK-1521498 free base,GSK1521498 free base
[1,1'-Biphenyl]-4-methanamine, N-(2,3-dihydro-1H-inden-2-yl)-3,5-difluoro-3'-(1H-1,2,4-triazol-5-yl)- | [Molecular Formula]
C24H20F2N4 | [MDL Number]
MFCD28502066 | [MOL File]
1007573-18-3.mol | [Molecular Weight]
402.44 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 11.36 mg/mL (28.23 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base has the potential for disorders of compulsive consumption of food, alcohol, and agents[1]. | [IC 50]
μ Opioid Receptor/MOR | [References]
[1] Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92. DOI:10.1038/npp.2015.152 |
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| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
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