| Identification | Back Directory | [Name]
N-{[3,5-difluoro-3'-(1H-1,2,4-triazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-2,3-dihydro-1H-inden-2-amine hydrochloride | [CAS]
1007578-24-6 | [Synonyms]
GSK1521498 free base (hydrochloride)
N-{[3,5-difluoro-3'-(1H-1,2,4-triazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-2,3-dihydro-1H-inden-2-amine hydrochloride | [EINECS(EC#)]
629-879-4 | [Molecular Formula]
C24H21ClF2N4 | [MDL Number]
MFCD32201044 | [MOL File]
1007578-24-6.mol | [Molecular Weight]
438.9 |
| Hazard Information | Back Directory | [Uses]
GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food, alcohol, and agents[1]. | [IC 50]
μ Opioid Receptor/MOR | [References]
[1] Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92. DOI:10.1038/npp.2015.152 |
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MedChemExpress
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www.medchemexpress.com |
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