| Identification | Back Directory | [Name]
D-ALA-GLY-PHE-MET-NH2 ACETATE SALT | [CAS]
100929-65-5 | [Synonyms]
d-ala-gly-phe-met-nh2
D-Ala-Gly-Phe-Met-NH2 monoacetate
D-ALA-GLY-PHE-MET-NH2 ACETATE SALT
des-tyr1,(D-ala2)-methionine*enkephalinamide acet
DES-TYR1,(D-ALA2)-METHIONINE*ENKEPHALINA MIDE ACETAT
(des-tyrosine1,D-alanine2)methionine enkephalinamide
DES-TYR1,[D-ALA2]-METHIONINE ENKEPHALINAMIDE ACETATE SALT | [Molecular Formula]
C21H33N5O6S | [MDL Number]
MFCD00133256 | [MOL File]
100929-65-5.mol | [Molecular Weight]
483.58 |
| Hazard Information | Back Directory | [Uses]
D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist[1]. | [in vivo]
D-Ala-Gly-Phe-Met-NH2 monoacetate (7.1 nM and 14.2 nM (0.5 μL); microinjection; male Sprague-Dawley rats) increases ethanol intake in preference to food in the nucleus accumbens (NAc)[1]. | Animal Model: | Male Sprague-Dawley rats (200-250 g)[1] | | Dosage: | 7.1 nM and 14.2 nM (0.5 μL) | | Administration: | Microinjection in the nucleus accumbens (NAc) | | Result: | Increased ethanol intake in the nucleus accumbens (NAc). |
| [References]
[1] Barson JR, et, al. Opioids in the nucleus accumbens stimulate ethanol intake. Physiol Behav. 2009 Oct 19;98(4):453-9. DOI:10.1016/j.physbeh.2009.07.012 |
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