| Identification | Back Directory | [Name]
2':3'-CYCLIC NADP SODIUM SALT | [CAS]
100929-77-9 | [Synonyms]
2':3'-cyclic nadp
2':3'-CYCLIC NADP SODIUM SALT
2',3'-cyclic NADP+ (sodium salt)
B-nicotinamide adenine dinucleotide*2':3'-cyclic
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT
β-nicotinamide adenine dinucleotide 2':3'-cyclic monophosphate disodium salt hydrate
β-Nicotinamide adenine dinucleotide 2μ:3μ-cyclic monophosphate hydrate disodium salt
Adenosine5'-(trihydrogen diphosphate), cyclic 2',3'-(hydrogen phosphate), P'→5'-ester with3-(aminocarbonyl)-1-b-D-ribofuranosylpyridinium inner salt, disodium salt | [Molecular Formula]
C21H25N7NaO16P3 | [MDL Number]
MFCD00063553 | [MOL File]
100929-77-9.mol | [Molecular Weight]
747.37 |
| Hazard Information | Back Directory | [Uses]
2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme abundant in myelin. It has been used in a coupled enzyme assay to quantify CNP activity. 2',3'-Cyclic NADP disodium (5 μM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria. | [References]
[1] Sogin, et al. 2',3'-Cyclic NADP as a substrate for 2',3'-cyclic nucleotide 3'-phosphohydrolase. J. Neurochem. 27(6), 1333-1337 (1976). |
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