| Identification | Back Directory | [Name]
RTIL 13 | [CAS]
1009376-10-6 | [Synonyms]
RTIL 13
4-(N,N-Dimethyl-N-octadecyl-N-ethyl)-4-aza-10-oxatricyclo-[5.2.1]decane-3,5-dionebromide | [Molecular Formula]
C30H55BrN2O3 | [MOL File]
1009376-10-6.mol | [Molecular Weight]
571.69 |
| Hazard Information | Back Directory | [Uses]
RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC50 of 2.3 μM for dynamin I GTPase. RTIL 13 also targets pleckstrin homology lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[1][2]. | [References]
[1] Zhang J, et, al. From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs. New Journal of Chemistry. 2008 Jan; 32(1): 1-180.
[2] Ascent Scientific Launch Novel Dynamin Inhibitor Dyngo-4a? with Children's Medical Research Institute and University of Newcastle. Tuesday, December 28, 2021. |
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| Company Name: |
Abcam Limited
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| Tel: |
021-2070050 400921018 |
| Website: |
www.abcam.cn |
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