| Identification | Back Directory | [Name]
3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE | [CAS]
10135-38-3 | [Synonyms]
TMPO
M4PO
3,3,5,5-TETRAMETHYL-PYRROLINE-N-OXIDE
3,3,5,5-Tetramethyl-1-pyrolline-N-oxide
3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE
3,3,5,5-Tetramethyl-1-pyrroline 1-oxide
3,3,5,5-Tetramethylpyrroline-N-oxide,98%
3,3,5,5-Tetramethyl-1-pyrroline N-oxide 95%
3,3,5,5-Tetramethyl-1-pyrroline N-Oxide
3,3,5,5-Tetramethyl-4,5-dihydro-3H-pyrrole 1-oxide
1-Oxylato-3,3,5,5-tetramethyl-4,5-dihydro-3H-pyrrole-1-ium | [Molecular Formula]
C8H15NO | [MDL Number]
MFCD00010542 | [MOL File]
10135-38-3.mol | [Molecular Weight]
141.21 |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow adhering crystalline chunks | [Melting point ]
58-61 °C(lit.)
| [Boiling point ]
73 °C1 mm Hg(lit.)
| [density ]
0.9938 (rough estimate) | [refractive index ]
1.4610 (estimate) | [storage temp. ]
0-6°C | [solubility ]
DMSO: Soluble: = 10 mg/ml
Ethanol: Soluble: = 10 mg/mlPBS (pH 7.2): Soluble: = 10 mg/ml | [form ]
powder to crystal | [pka]
2.50±0.60(Predicted) | [color ]
White to Orange to Green | [CAS DataBase Reference]
10135-38-3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow adhering crystalline chunks | [Uses]
TMPO is a pyrroline-based N-oxyl spin trap. TMPO is described for use as a cell-permeable spin trap probe for ESR studies of biological systems. | [General Description]
The ESR spectrum of 3,3,5,5-tetramethyl-1-pyrroline N-oxide was studied. | [References]
[1] GARRY R. BUETTNER Bradley E B. The spin trapping of superoxide with M4PO (3,3,5,5-Tetramethylpyrroline-N-oxide)[J]. Free Radical Biology and Medicine, 1990, 8 1: Pages 57-60. DOI: 10.1016/0891-5849(90)90145-9
[2] MICHAEL J. DAVIES Sarah L S Luigi G Forni. Electron spin resonance and pulse radiolysis studies on the spin trapping of sulphur-centered radicals[J]. Chemico-Biological Interactions, 1987, 61 2: Pages 177-188. DOI: 10.1016/0009-2797(87)90038-x
[3] A F SLATER. Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis.[J]. Biochemical Journal, 1995, 306 ( Pt 3): 771-778. DOI: 10.1042/bj3060771 |
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