| Identification | Back Directory | [Name]
7-[4-(4,6-dimethylpyrimidin-2-yl)piperazin-1-yl]-2-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine | [CAS]
1015582-31-6 | [Synonyms]
SARS-CoV-2 nsp13-IN-3
7-[4-(4,6-dimethylpyrimidin-2-yl)piperazin-1-yl]-2-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine
Pyrazolo[1,5-a]pyrimidine, 7-[4-(4,6-dimethyl-2-pyrimidinyl)-1-piperazinyl]-2-(2-methoxyphenyl)-5-methyl- | [Molecular Formula]
C24H27N7O | [MOL File]
1015582-31-6.mol | [Molecular Weight]
429.52 |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2 nsp13-IN-3 (Compound C3) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 32 μM against nsp13 ssDNA+ ATPase[1]. | [References]
[1] Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13. DOI:10.1021/acsinfecdis.2c00165 |
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