| Identification | Back Directory | [Name]
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- | [CAS]
1016866-61-7 | [Synonyms]
6-(4-phenylpiperazin-1-yl)pyridine-3-carboxamidine
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- | [Molecular Formula]
C16H19N5 | [MOL File]
1016866-61-7.mol | [Molecular Weight]
281.36 |
| Hazard Information | Back Directory | [Uses]
C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a Kd of 9.8 μM[1]. | [References]
[1] Xu X, et al. Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs. J Immunol. 2024 Feb 15;212(4):689-701. DOI:10.4049/jimmunol.2300630 |
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