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101758-79-6

101758-79-6 Structure

101758-79-6 Structure
IdentificationBack Directory
[Name]

(3aR)-3,3aβ,4,5,6,6aβ-Hexahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-3-(4α-propylcyclohexan-1α-yl)-1-propenyl]cyclopenta[b]pyrrole-2-pentanoic acid methyl ester
[CAS]

101758-79-6
[Synonyms]

(3aR)-3,3aβ,4,5,6,6aβ-Hexahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-3-(4α-propylcyclohexan-1α-yl)-1-propenyl]cyclopenta[b]pyrrole-2-pentanoic acid methyl ester
[Molecular Formula]

C25H41NO4
[MDL Number]

MFCD30738673
[MOL File]

101758-79-6.mol
[Molecular Weight]

419.6
Chemical PropertiesBack Directory
[Boiling point ]

532.2±50.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[pka]

14.22±0.20(Predicted)
Hazard InformationBack Directory
[Description]

OP-2507 is a prostacyclin agonist potentially for the treatment of hepatic insufficiency and hypertension.
[Uses]

OP-2507 is a prostacyclin analog. OP-2507 can increase brain glucose levels in mice, suppress the breakdown of energy metabolism under hypoxic conditions, and has a protective effect against changes in cyclic nucleotides in hypoxic brain tissue (specifically, an increase in cyclic AMP and a decrease in cyclic GMP). OP-2507 provides protective effects against brain hypoxia and edema[1].
[References]

[1] Masuda Y, et al. Protective effect of a new prostacyclin analogue OP-2507 against cerebral anoxia and edema in experimental animals. Eur J Pharmacol. 1986 Apr 29;123(3):335-44. DOI:10.1016/0014-2999(86)90706-5
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