| Identification | Back Directory | [Name]
gitoformate | [CAS]
10176-39-3 | [Synonyms]
AC 2770
Formiloxin
gitoformate
Gitoformatum
pentaformylgitoxin
gitoxin pentaformate
Card-20(22)-enolide, 3-[(O-2,6-dideoxy-3,4-di-O-formyl-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-formyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-formyl-β-D-ribo-hexopyranosyl)oxy]-16-(formyloxy)-14-hydroxy-, (3β,5β,16β)- | [EINECS(EC#)]
233-450-3 | [Molecular Formula]
C46H64O19 | [MDL Number]
MFCD01740179 | [MOL File]
10176-39-3.mol | [Molecular Weight]
920.993 |
| Chemical Properties | Back Directory | [Boiling point ]
723.06°C (rough estimate) | [density ]
1.1638 (rough estimate) | [refractive index ]
1.6500 (estimate) | [pka]
14.20±0.70(Predicted) |
| Safety Data | Back Directory | [RIDADR ]
2811 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 orl-rat: 39,010 mg/kg MDACAP15,407,79 |
| Hazard Information | Back Directory | [Uses]
Gitoformate (AC 2770) is a semisynthetic cardiac glycoside. Gitoformate can be used for renal function research[1]. | [Safety Profile]
A poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors. | [References]
[1] R.Schmitt-Rüth, et al. Plasma Concentration Measurement and Clinical Parameters in a Geriatric Population Treated for Cardiac Insufficiency Using the Nonrenal-Dependent Cardiac Glycoside Pentaformylgitoxin (Gitoformate). Springer Berlin Heidelberg, 1986. |
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