| | Identification | Back Directory |  | [Name] 
 2,2'-BIPYRAZINE
 |  | [CAS] 
 10199-00-5
 |  | [Synonyms] 
 2,2'-Bipyrazyl
 2,2'-BIPYRAZINE
 2,2'-Bipyrazinyl
 2,2'-Bipyrazine >
 2-pyrazin-2-ylpyrazine
 |  | [Molecular Formula] 
 C8H6N4
 |  | [MDL Number] 
 MFCD00010288
 |  | [MOL File] 
 10199-00-5.mol
 |  | [Molecular Weight] 
 158.16
 | 
 | Chemical Properties | Back Directory |  | [Melting point ] 
 185.0 to 189.0 °C
 |  | [Boiling point ] 
 299.0±35.0 °C(Predicted)
 |  | [density ] 
 1.239±0.06 g/cm3(Predicted)
 |  | [form ] 
 solid
 |  | [pka] 
 -0.63±0.10(Predicted)
 |  | [color ] 
 light-brown
 |  | [Sensitive ] 
 air sensitive
 |  | [λmax] 
 320nm(Hexane)(lit.)
 |  | [CAS DataBase Reference] 
 10199-00-5
 | 
 | Hazard Information | Back Directory |  | [Description] 
 2,2'-Bipyrazine is an organic compound containing two pyridine rings and belongs to a group of multifunctional drugs with anti-inflammatory properties. It has shown promising pharmacological effects on several aspects of inflammation, oxidative stress and tumors.
 |  | [Uses] 
 2,2′-Bipyrazine (bpz) can be used as a ligand to synthesize strongly oxidizing photocatalysts. Ruthenium-based homoleptic tris(bipyrazyl) complex [(Ru(bpz)32+] derived from 2,2′-bipyrazine ligand can be used as an effective photocatalyst for oxidatively induced organic transformations. For instance, [(Ru(bpz)32+] is capable of promoting radical cation mediated Diels–Alder cycloadditions, radical thiol-ene couplings, photooxygenation reactions, and [3+2] cycloaddition reactions.
 |  | [reaction suitability] 
 core: palladium
 reaction type: Buchwald-Hartwig Cross Coupling Reaction
 reaction type: Heck Reaction
 reaction type: Hiyama Coupling
 reaction type: Negishi Coupling
 reaction type: Sonogashira Coupling
 reaction type: Stille Coupling
 reaction type: Suzuki-Miyaura Coupling
 reagent type: catalyst
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