| Identification | Back Directory | [Name]
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE TRIS SALT | [CAS]
102029-77-6 | [Synonyms]
CAMP TRIS SALT
cAMP, cyclic AMP
CYCLIC AMP TRIS SALT
-cyclicMonophosphateTrisSalt
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE TRIS
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE TRIS SALT | [Molecular Formula]
C14H23N6O9P | [MDL Number]
MFCD00058346 | [MOL File]
102029-77-6.mol | [Molecular Weight]
450.34 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: 100 mg/mL | [form ]
powder | [color ]
white | [biological source]
synthetic | [Water Solubility ]
H2O: 100mg/mL |
| Hazard Information | Back Directory | [Uses]
Adenosine 3′,5′-cyclic monophosphate tris salt has been used as a medium supplement for human endometrial stromal cells (hESCs) culture and induced neural stem cells (iNSCs). It has been used in the spectroscopic characterization of pink flamindo, a red cAMP indicator. | [General Description]
Adenosine 3′,5′-cyclic monophosphate (cAMP) is synthesized from ATP in the presence of Adenylate cyclase enzyme. cAMP is majorly used as a marker in immunochemical detection assays. Intracellular levels of cAMP control immune and inflammatory functions. Bacterial infection triggers intracellular cAMP production. Elevated levels of cAMP modulates mitogen-activated protein kinase (MAPK) in cancer. An altered cAMP level is implicated in pathogenesis of cataract and cardiovascular disease. A decrease in cAMP levels triggers impaired insulin secretion in diabetes. | [Biochem/physiol Actions]
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|