| Identification | Back Directory | [Name]
2-BROMO-6-FLUOROBENZOYL CHLORIDE | [CAS]
1020718-20-0 | [Synonyms]
2-BROMO-6-FLUOROBENZOYL CHLORIDE
Benzoyl chloride, 2-bromo-6-fluoro- | [Molecular Formula]
C7H3BrClFO | [MDL Number]
MFCD09038470 | [MOL File]
1020718-20-0.mol | [Molecular Weight]
237.45 |
| Chemical Properties | Back Directory | [Boiling point ]
236℃ | [density ]
1.742 | [Fp ]
97℃ | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
liquid | [color ]
Colourless |
| Hazard Information | Back Directory | [Synthesis]
General method: 2-bromo-6-fluorobenzoic acid (1.0 mmol) was mixed with excess thionyl chloride (5 mL) and reacted at reflux for 2 hours. After completion of the reaction, the excess thionyl chloride was removed by vacuum concentration to give 2-bromo-6-fluorobenzoyl chloride in quantitative yield. | [References]
[1] Chinese Chemical Letters, 2013, vol. 24, # 8, p. 673 - 676
[2] Patent: EP2123644, 2009, A1. Location in patent: Page/Page column 59
[3] Journal of the American Chemical Society, 2010, vol. 132, # 32, p. 11278 - 11287
[4] Synlett, 2013, vol. 24, # 19, p. 2575 - 2580
[5] Journal of the American Chemical Society, 2017, vol. 139, # 30, p. 10228 - 10231 |
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