| Hazard Information | Back Directory | [Description]
RID-F is a nonpeptidic proteasome inhibitor. | [Uses]
RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively[1]. | [References]
[1] Hasegawa M, et, al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2014 Jan:71:290-305. DOI:10.1016/j.ejmech.2013.11.009 |
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