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1021106-40-0

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1021106-40-0 Structure

1021106-40-0 Structure
IdentificationBack Directory
[Name]

3-Pyridinesulfonamide, N-[(4-chlorophenyl)methyl]-N-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-
[CAS]

1021106-40-0
[Synonyms]

IXA6
3-Pyridinesulfonamide, N-[(4-chlorophenyl)methyl]-N-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-
[Molecular Formula]

C22H20ClN3O3S
[MOL File]

1021106-40-0.mol
[Molecular Weight]

441.93
Chemical PropertiesBack Directory
[Boiling point ]

692.0±65.0 °C(Predicted)
[density ]

1.395±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

2.02±0.11(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1].
[References]

[1] Julia M D Grandjean, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020 Oct;16(10):1052-1061. DOI:10.1038/s41589-020-0584-z
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