| Identification | Back Directory | [Name]
2-Amino-1-beta-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone | [CAS]
10212-31-4 | [Synonyms]
4(1H)-Pyrimidinone, 2-amino-1-β-D-arabinofuranosyl-5-methyl-
2-Amino-1-beta-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinon
2-Amino-1-beta-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone | [Molecular Formula]
C10H15N3O5 | [MDL Number]
MFCD30718547 | [MOL File]
10212-31-4.mol | [Molecular Weight]
257.24 |
| Hazard Information | Back Directory | [Uses]
2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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