| Identification | Back Directory | [Name]
8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT | [CAS]
102185-14-8 | [Synonyms]
8-N3-ADP SODIUM SALT
8-Azido-ADP disodium
-diphosphateSodiumSalt
8-Azidoadenosine-5&rsquo
8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT
8-Azidoadenosine-5'-diphosphate Sodium Salt
8-azidoadenosine-5’-o-diphosphate(8-n3-adp),sodiumsalt | [Molecular Formula]
C10H13N8NaO10P2 | [MDL Number]
MFCD02091658 | [MOL File]
102185-14-8.mol | [Molecular Weight]
490.2 |
| Hazard Information | Back Directory | [Uses]
8-Azido-ADP (disodium) is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP (disodium) causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP (disodium) inhibits the normal state 4 → 3 transitions of mitochondrial respiration induced by ADP[1]. 8-Azido-ADP (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] SchHafer G, et al. 8-azido-ADP, a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. FEBS Lett. 1976 Apr 15;64(1):185-9. DOI:10.1016/0014-5793(76)80279-7 |
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| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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