| Identification | Back Directory | [Name]
IMETIT DIHYDROBROMIDE | [CAS]
102203-18-9 | [Synonyms]
imetit IMETIT DIHYDROBROMIDE 2-[2-(1H-imidazol-5-yl)ethyl]isothiourea 2-[2-(1H-Imidazol-4-yl)-ethyl]-isothiourea 2-(1H-Imidazol-4-yl)ethyl carbamimidothioate 2-(1H-imidazol-5-yl)ethyl carbamimidothioate 5-[2-(IMIDAZOL-4-YL)ETHYL]ISOTHIOUREA DIHYDROBROMIDE S-[2-(IMIDAZOL-4-YL)ETHYL]ISOTHIOUREA DIHYDROBROMIDE CarbaMiMidothioic acid, 2-(1H-iMidazol-5-yl)ethyl ester | [Molecular Formula]
C6H10N4S | [MDL Number]
MFCD00153816 | [MOL File]
102203-18-9.mol | [Molecular Weight]
170.24 |
| Hazard Information | Back Directory | [Uses]
Imetit dihydrobromide is a high affinity agonist at the histamine H3- and H4-receptors. | [Definition]
ChEBI: An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are
0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration. |
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