| Chemical Properties | Back Directory | [Boiling point ]
524.359±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.285±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
DMSO: Soluble: = 10 mg/ml
Ethanol: Soluble: = 10 mg/ml | [form ]
Solid | [pka]
6.962±0.50(predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1]. | [References]
[1] Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12. DOI:10.1016/j.chembiol.2023.06.026 |
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