1025023-04-4

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1025023-04-4 Structure

Identification	Back Directory
[Name] Periglaucine A
[CAS] 1025023-04-4
[Synonyms] Periglaucine A Hasubanan-6-one, 8,10-epoxy-7,8-dimethoxy-17-methyl-2,3-[methylenebis(oxy)]-, (7α,8β,10β)- (7alpha,8beta,10beta)-8,10-Epoxy-7,8-dimethoxy-17-methyl-2,3-[methylenebis(oxy)]hasubanan-6-one
[Molecular Formula] C20 H23 N O6
[MOL File] 1025023-04-4.mol
[Molecular Weight] 373.4

Hazard Information	Back Directory
[Uses] Periglaucine A, a hasubanane-type alkaloid, can be isolated from Pericampylus glaucus. Periglaucine A can inhibits HBV surface antigen (HBsAg) secretion in Hep G2.2.15 cells. Periglaucine A also shows anti-HIV-1 activity in C8166 cells (EC50: 204 μM)[1].
[Definition] ChEBI:Periglaucine A is an isoquinoline alkaloid. It has a role as a metabolite.
[References] [1] Yan MH, et al. Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus. J Nat Prod. 2008 May;71(5):760-3. DOI:10.1021/np070479+

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