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1025023-05-5

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1025023-05-5 Structure

1025023-05-5 Structure
IdentificationBack Directory
[Name]

Periglaucine B
[CAS]

1025023-05-5
[Synonyms]

Periglaucine B
(7beta,8beta,10beta)-8,10-Epoxy-7,8-dimethoxy-17-methyl-2,3-[methylenebis(oxy)]-hasubanan-6-one
[Molecular Formula]

C20H23NO6
[MDL Number]

MFCD22417307
[MOL File]

1025023-05-5.mol
[Molecular Weight]

373.4
Chemical PropertiesBack Directory
[Boiling point ]

509.5±50.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[pka]

6.65±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

Periglaucine B ((+)-Periglaucine B) is an alkaloid and an HBsAg inhibitor. Periglaucine B can be isolated from Pericampylus glaucus. Periglaucine B inhibits the secretion of hepatitis B virus (HBV) surface antigen (HBsAg) in Hep G2.2.15 cells with an IC50 of 0.47 mM[1].
[Definition]

ChEBI: Periglaucine B is an isoquinoline alkaloid. It has a role as a metabolite.
[References]

[1] Yan MH, et al. Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus. J Nat Prod. 2008 May;71(5):760-3. DOI:10.1021/np070479+
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