| Identification | Back Directory | [Name]
5-(4-chlorophenyl)-N-{[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl}pyridine-3-carboxamide | [CAS]
1026822-49-0 | [Synonyms]
Nav1.8-IN-1
CHEMBL1270208
5-(4-chlorophenyl)-N-((2-(2,2,2-trifluoroethoxy)pyridin-3-
yl)methyl)nicotinamide
5-(4-chlorophenyl)-N-{[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl}pyridine-3-carboxamide
3-Pyridinecarboxamide, 5-(4-chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)-3-pyridinyl]methyl]-
Na channels,Nav1.8IN1,Inhibitor,inflammatory,Nav1.8 IN 1,Na(v)1.8,Sodium Channel,Na+ channels,neuropathic pain,inhibit | [Molecular Formula]
C20H15ClF3N3O2 | [MOL File]
1026822-49-0.mol | [Molecular Weight]
421.8 |
| Hazard Information | Back Directory | [Uses]
Nav1.8-IN-1 (Compound 31) is a potent inhibitor of Na(v)1.8 sodium channel. Nav1.8-IN-1 has the potential for the research of inflammatory and neuropathic pain[1]. | [References]
[1] Kort ME, et al. Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorg Med Chem Lett. 2010;20(22):6812-6815. DOI:10.1016/j.bmcl.2010.08.121 |
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Enamine Ltd
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+1 732 274 9150 |
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www.enaminestore.com |
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