| Identification | Back Directory | [Name]
H-DAB(BOC)-OH | [CAS]
10270-94-7 | [Synonyms]
Dab(Boc)-OH
H-DAB(BOC)-OH
L-Dab(Boc)-OH
H-Daba(Boc)-OH
H-L-Daba(Boc)-OH
N-GAMMA-BOC-L-2,4-DIAMINOBUTYRIC ACID
(S)-2-Amino-4-(Boc-amino)butanoic acid
ALPHA,GAMMA-DIAMINOBUTYRIC ACID(BOC)-OH
Nγ-Boc-L-2,4-diaminobutyric acid≥ 99% (HPLC)
(S)-2-amino-4-(tert-butoxycarbonylamino)butanoic acid
(2S)-Amino-4-[(tert-butoxycarbonyl)amino]butanoic acid
(2S)-2-amino-4-{[(tert-butoxy)carbonyl]amino}butanoic acid
N-GAMMA-T-BUTOXYCARBONYL-L-ALPHA,GAMMA-DIAMINOBUTYRIC ACID
(2S)-2-Amino-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-Butanoic Acid
(2S)-2-amino-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Butanoic acid, 2-amino-4-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2S)- | [Molecular Formula]
C9H18N2O4 | [MDL Number]
MFCD00236842 | [MOL File]
10270-94-7.mol | [Molecular Weight]
218.25 |
| Chemical Properties | Back Directory | [Melting point ]
216℃ | [Boiling point ]
388.2±37.0 °C(Predicted) | [density ]
1.160±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [form ]
Solid | [pka]
2.25±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities[1]. | [References]
[1] Rosowsky, et al. "Methotrexate analogs. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogs containing a basic amino acid side chain." Journal of medicinal chemistry 29.5 (1986): 655-660. DOI:10.1021/jm00155a012 |
|
|