| Identification | Back Directory | [Name]
3-(6-Hydroxy-2-naphthalenyl)-1H-indole-5-carboxylic acid | [CAS]
1027786-12-4 | [Synonyms]
3-(6-Hydroxy-2-naphthalenyl)-1H-indole-5-carboxylic acid | [Molecular Formula]
C19H13NO3 | [MOL File]
1027786-12-4.mol | [Molecular Weight]
303.31 |
| Chemical Properties | Back Directory | [Boiling point ]
648.6±50.0 °C(Predicted) | [density ]
1.429±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
4.34±0.30(Predicted) | [color ]
Gray to dark gray |
| Hazard Information | Back Directory | [Uses]
QR-0217 is a potent Aβ1-40 aggregation inhibitor with an IC50 value of 7.5 μM. QR-0217 inhibits α-synuclein aggregation. QR-0217 reduces memory impairments caused by Aβ neurotoxicity[1]. | [References]
[1] Michael D. Carter, et al. Compounds and methods for treating protein folding disorders. US8362066B2. |
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