| Identification | Back Directory | [Name]
N,O-DIDANSYL-L-TYROSINE MONOCYCLOHEXYLAMMONIUM SALT | [CAS]
102783-47-1 | [Synonyms]
N,O-DIDANSYL-L-TYROSINE CYCLOHEXYLAMMONIUM
N,O-DIDANSYL-L-TYROSINE MONOCYCLOHEXYLAM MONIUM
n,o-didansyl-l-tyrosine cyclohexylammonium salt
N,O-DIDANSYL-L-TYROSINE MONOCYCLOHEXYLAMMONIUM SALT | [Molecular Formula]
C39H46N4O7S2 | [MDL Number]
MFCD00058031 | [MOL File]
102783-47-1.mol | [Molecular Weight]
746.94 |
| Hazard Information | Back Directory | [Uses]
N,O-Didansyl-L-tyrosine cyclohexylammonium is a potent selective thymidylate synthase (TS) inhibitor, acts on TS of Escherichia coli, Lactobacillus casei and human with the IC50 values of 5.0, 3.4 and 119 μM, respectively[1]. | [References]
[1] T A Fritz, et al. Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase. Chem Biol. 2001 Oct;8(10):981-95. DOI:10.1016/s1074-5521(01)00067-9 |
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