ChemicalBook--->CAS DataBase List--->102917-80-6

102917-80-6

102917-80-6 Structure

102917-80-6 Structure
IdentificationBack Directory
[Name]

(2S,3R,4E)-N-TETRACOSANOYL SPHINGOSINE
[CAS]

102917-80-6
[Synonyms]

C24 CERAMIDE
24:0 CERAMIDE
C24 Ceramide (d18:1/24:0)
N-TETRACOSANOYL-D-SPINGOSINE
N-LIGNOCEROYL-D-ERYTHRO-SPHINGOSINE
(2S,3R,4E)-N-TETRACOSANOYL SPHINGOSINE
N-LIGNOCEROYL-D-ERYTHRO-SPHINGOSINE;C24 CERAMIDE (D18:1/24:0)
[R-(R*,S*)]-N-[2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-tetracosanamide
Tetracosanamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-(R*,S*)]- (9CI)
[Molecular Formula]

C42H83NO3
[MDL Number]

MFCD02259276
[MOL File]

102917-80-6.mol
[Molecular Weight]

650.11
Chemical PropertiesBack Directory
[Boiling point ]

750.0±60.0 °C(Predicted)
[density ]

0.906±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

13.82±0.20(Predicted)
[color ]

White to off-white
[InChIKey]

ZJVVOYPTFQEGPH-AUTSUKAISA-N
[SMILES]

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
Safety DataBack Directory
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

C24 Ceramide (d18:1/24:0) has been used:
  • in the generation of small unilamellar vesicles
  • as an internal standard in liquid chromatography-mass spectrometry for ceramide quantification from r at samples
  • to test its effect on mitochondrial stress response in worms

[Biological Activity]

C24 ceramide induces mitochondrial stress response. Its levels are depleted in coronary artery disease (CAD). Howeverelevated ceramide levels is observed in Alzheimerμs disease. C24 is synthesized during stress. It mediates spontaneous neutrophil death.
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