| Identification | Back Directory | [Name]
propioxatin B | [CAS]
102962-95-8 | [Synonyms]
propioxatin B
Propioxantin B
1-[(R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-L-Pro-L-Val-OH
N-[1-[(R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-L-prolyl]-L-valine
L-Valine, 1-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-L-prolyl- (9CI) | [Molecular Formula]
C18H31N3O6 | [MOL File]
102962-95-8.mol | [Molecular Weight]
385.46 |
| Hazard Information | Back Directory | [Uses]
Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo. | [References]
[1] Propioxatins A and B, new enkephalinase B inhibitors. II. Structural elucidation |
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