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1031993-35-7

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1031993-35-7 Structure

1031993-35-7 Structure
IdentificationBack Directory
[Name]

1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]-
[CAS]

1031993-35-7
[Synonyms]

A1AR antagonist 4
1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]-
[Molecular Formula]

C23H25N3O2
[MOL File]

1031993-35-7.mol
[Molecular Weight]

375.46
Chemical PropertiesBack Directory
[Boiling point ]

568.8±50.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[pka]

13.94±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

A1AR antagonist 4 (compound 22) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.51 and a pKi of 6.29[1].
[IC 50]

hA1AR: 6.29 (pKi); hA2AAR: <4 (pKi)
[References]

[1] Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936. DOI:10.1016/j.ejmech.2019.111936
1031993-35-7 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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