1032347-93-5

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1032347-93-5 Structure

Identification	Back Directory
[Name] Thio-PEG12-acid
[CAS] 1032347-93-5
[Synonyms] SH-PEG12-COOH HS-PEG12-COOH Thio-PEG18-acid Thio-PEG12-acid Thiol-PEG12-acid HS-PEG12-CH2CH2COOH Thiol-PEG12-propionic acid α-Mercapto-ω-carboxy Polyethylene Glycol
[Molecular Formula] C27H54O14S
[MDL Number] MFCD21363238
[MOL File] 1032347-93-5.mol
[Molecular Weight] 634.774

Chemical Properties	Back Directory
[storage temp. ] Refrigerator
[solubility ] DMSO (Slightly), Methanol (Slightly)
[form ] Oil
[color ] Colourless to Light Yellow Sitcky

Hazard Information	Back Directory
[Description] Thiol-PEG12-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
[Uses] Thio-PEG12-acid can form conjugates with gold nanoparticles to be used in neuroimaging and drug delivery.

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