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103828-81-5

103828-81-5 Structure

103828-81-5 Structure
IdentificationBack Directory
[Name]

LY 207702
[CAS]

103828-81-5
[Synonyms]

LY 207702
[Molecular Formula]

C10H12F2N6O3
[MOL File]

103828-81-5.mol
[Molecular Weight]

302.24
Chemical PropertiesBack Directory
[Boiling point ]

725.3±70.0 °C(Predicted)
[density ]

2.17±0.1 g/cm3(Predicted)
[pka]

11.40±0.70(Predicted)
Hazard InformationBack Directory
[Description]

LY 207702 is a difluorinated purine nucleoside that exhibits antitumor activity in preclinical models.
[Uses]

LY207702 is a difluorinated purine nucleoside with antitumor activity and cardiotoxicity. LY207702 is cytotoxic to CEA-positive LS174T cells (IC50=0.302 μg/mL). LY207702 can be used in the study of colon cancer[1].
[References]

[1] Patel V F, et al. Novel acid labile COL1 trityl-linked difluoronucleoside immunoconjugates: synthesis, characterization, and biological activity1[J]. Bioconjugate chemistry, 1996, 7(4): 497-510. DOI:10.1021/bc960038u
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Company Name: TargetMol Chemicals Inc.
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