| Identification | Back Directory | [Name]
sodium (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(E)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | [CAS]
104146-53-4 | [Synonyms]
ME-1206
Cefditoren sodium
Cefditoren D3 Sodium
Cefditoren Sodium Salt
Cefditoren acid sodium salt
Cefditoren Pivoxil Impurity 15
Cefditoren Pivoxil Impurity 22
Cefditoren Acid Sodium Salt USP/EP/BP
3-[(Z)-2-(4-Methylthiazol-5-yl)vinyl]-7β-[[(Z)-(2-aminothiazol-4-yl)(methoxyimino)acetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt
sodium (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((Z)-2-(4-methylthiazol-5-yl)vinyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetylamino]-3-[(Z)-2-(4-methyl-5-thiazolyl)vinyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid sodium salt
sodium (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(E)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-,sodium salt (1:1), (6R,7R)-
(6R-(3(Z),6alpha,7beta(Z)))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monosodium salt
Cefditoren SodiumQ: What is
Cefditoren Sodium Q: What is the CAS Number of
Cefditoren Sodium Q: What is the storage condition of
Cefditoren Sodium Q: What are the applications of
Cefditoren Sodium | [Molecular Formula]
C19H18N6NaO5S3+ | [MDL Number]
MFCD01750404 | [MOL File]
104146-53-4.mol | [Molecular Weight]
528.56 |
| Chemical Properties | Back Directory | [storage temp. ]
4°C, away from moisture | [solubility ]
DMSO : 31.25 mg/mL (59.12 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
White to light yellow | [Water Solubility ]
H2O: 2mg/mL, clear (Warmed) |
| Hazard Information | Back Directory | [Uses]
Third generation cephalosporin; active metabolite of orally absorbed pivaloyloxymethyl ester prodrug. An antibacterial. | [Biological Activity]
Cefditoren sodium is orally availablebroad spectrum third-generation cephalosporin antibiotic. Cefditoren sodium is active against both gram-negative and gram-positive bacteria. It is commonly used for treatment of chronic bronchitiscommunity-acquired pneumoniapharyngitis/tonsillitisand uncomplicated skin and skin-structure infections. | [in vivo]
Pharmacokinetics in mice[1]:
| Cefditoren (mg/kg) | C0 (μg/ml) | t1/2 (h) | AUClast (μg× h/ml) | Tlast (h) | | 6.25 | 53.0 | 0.9 | 30.4 | 6 | | 12.5 | 168.4 | 1.1 | 64.1 | 8 | | 25 | 232.5 | 0.9 | 101.3 | 8 | | 50 | 290.6 | 1.1 | 124.4 | 8 |
| [storage]
4°C, away from moisture |
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