| Identification | Back Directory | [Name]
[4-[4-[3-Oxo-6′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3′-yl]-1-piperazinyl]butyl]triphenyl-phosphonium iodide | [CAS]
1041634-69-8 | [Synonyms]
MitoPY1
[4-[4-[3-Oxo-6′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3′-yl]-1-piperazinyl]butyl]triphenyl-phosphonium iodide | [Molecular Formula]
C52H53BN2O5P+ | [MOL File]
1041634-69-8.mol | [Molecular Weight]
827.79 |
| Hazard Information | Back Directory | [Description]
MitoPY1 is a targetable fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells, which displays enhanced emission at 528 nm in the presence of H2O2. | [Uses]
MitoPY1 has been used as a specific mitochondrial H2O2 probe to measure mitochondrial ROS (reactive oxygen species) level. | [Biochem/physiol Actions]
MiroPY1 is an irreversible and bifunctional dye. It employs a triphenylphosphonium targeting group and a boronate-based molecular switch to specifically respond to H2O2 over competing reactive oxygen species (ROS) in the mitochondria. It does not require transfection. MiroPY1 is photostable and limits false positives. | [storage]
Store at -20°C |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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