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1044503-04-9

1044503-04-9 Structure

1044503-04-9 Structure
IdentificationBack Directory
[Name]

LL 3858
[CAS]

1044503-04-9
[Synonyms]

LL 3858
Sudoterb HCl
LL-3858 dihydrchloride
Sudoterb (hydrochloride (1:2))
N-[2-methyl-5-phenyl-3-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]pyrrol-1-yl]pyridine-4-carboxamide:dihydrochloride
[Molecular Formula]

C29H29ClF3N5O
[MDL Number]

MFCD18633306
[MOL File]

1044503-04-9.mol
[Molecular Weight]

556.03
Hazard InformationBack Directory
[Uses]

Sudoterb (LL 3858) hydrochloride is an orally active anti-Tuberculosis agent[1].
[in vivo]

Sudoterb hydrochloride (12.5 mg/kg and 25 mg/kg, p.o., 4 and 8 weeks) is effective against M.tuberculosis in mice[2].
Sudoterb hydrochloride (p.o., mice) shows a LD50 of 700 mg/kg[2].

[References]

[1] Maha A. Elhakeem, et al. Synthesis and anti-mycobacterial evaluation of some new isonicotinylhydrazide analogues. Bulletin of Faculty of Pharmacy, Cairo University. 2015, 53 (1), 45-52
[2] Protopopova M, et al. In search of new cures for tuberculosis. Med Chem. 2007 May;3(3):301-16. DOI:10.2174/157340607780620626
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