| Identification | Back Directory | [Name]
ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-PRO-LEU-MET-NH2 | [CAS]
104486-69-3 | [Synonyms]
[Pro9]SP
RPKPQQFFPLM-NH2
pro(9)-substance
[PRO9] SUBSTANCE P
[TYR9]-SUBSTANCE P
substance P, Pro(9)-
9-L-PROLINE-SUBSTANCE P
Substance P,9-L-proline-
Pro9]-Substance P[Pro9]-
[Pro9]-Substance P
[Pro9]-Substance P, ≥97% (HPLC)
ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-PRO-LEU-MET-NH2
H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met-NH2
L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-L-Pro-L-Leu-L-Met-NH2
(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide | [Molecular Formula]
C66H102N18O13S | [MDL Number]
MFCD00214104 | [MOL File]
104486-69-3.mol | [Molecular Weight]
1387.69 |
| Hazard Information | Back Directory | [Uses]
[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM[1]. | [IC 50]
NK1: 0.93 nM (EC50) | [References]
[1] Petitet F, et al. Further demonstration that [Pro9]-substance P is a potent and selective ligand of NK-1 tachykinin receptors. J Neurochem. 1991 Mar;56(3):879-89. DOI:10.1111/j.1471-4159.1991.tb02004.x |
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