| Identification | Back Directory | [Name]
3-(3-TRIFLUOROMETHYL-PHENYL)-PROPYLAMINE | [CAS]
104774-87-0 | [Synonyms]
RARECHEM AL BW 1078
Cicalcet metabolite M4
Cinacalcet metabolite M4
Cinacalcet 3-TFM Amine Impurity
3-(TrifluoroMethyl)-benzenepropanaMine
Benzenepropanamine, 3-(trifluoromethyl)-
3-(3-TRIFLUOROMETHYL-PHENYL)-PROPYLAMINE
3-[3-(Trifluoromethyl)phenyl]-1-propanamine
3-(3-(TRIFLUOROMETHYL)PHENYL)PROPAN-1-AMINE | [Molecular Formula]
C10H12F3N | [MDL Number]
MFCD06213071 | [MOL File]
104774-87-0.mol | [Molecular Weight]
203.2 |
| Chemical Properties | Back Directory | [Boiling point ]
222.2±40.0 °C(Predicted) | [density ]
1.154±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Oil | [pka]
10.20±0.10(Predicted) | [color ]
Colourless |
| Hazard Information | Back Directory | [Uses]
Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2]. | [References]
[1] Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. DOI:10.1124/dmd.104.000604
[2] Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92. DOI:10.1038/sj.ki.5000324 |
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