| Identification | Back Directory | [Name]
4-O-Methylsappanol | [CAS]
104778-16-7 | [Synonyms]
4-O-Methylsappanol
(3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol
(3R,4S)-3-[(3,4-dihydroxyphenyl)methyl]-4-methoxy-2,4-dihydrochromene-3,7-diol
2H-1-Benzopyran-3,7-diol, 3-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-4-methoxy-, (3R,4S)- | [Molecular Formula]
C17H18O6 | [MDL Number]
MFCD32000847 | [MOL File]
104778-16-7.mol | [Molecular Weight]
318.32 |
| Hazard Information | Back Directory | [Uses]
4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana[1]. 4-O-Methylsappanol (EC50 of 4.6 μM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells[2]. | [References]
[1] V L Niranjan Reddy, et al. Inhibitory activity of homoisoflavonoids from Caesalpinia sappan against Beauveria bassiana. Fitoterapia. 2003 Sep;74(6):600-2. DOI:10.1016/s0367-326x(03)00153-9
[2] Kaoru Mitani, et al. Suppression of melanin synthesis by the phenolic constituents of sappanwood (Caesalpinia sappan). Planta Med. 2013 Jan;79(1):37-44. DOI:10.1055/s-0032-1327897 |
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