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1048021-78-8

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1048021-78-8 Structure

1048021-78-8 Structure
IdentificationBack Directory
[Name]

adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-
[CAS]

1048021-78-8
[Synonyms]

3'-azidomethyl-dATP
3′-O-Azidomethyl-dATP 100mM Sodium Solution
3'-azidomethyl-2'-Deoxyadenosine-5'-Triphosphate
adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-
[Molecular Formula]

C11H17N8O12P3
[MOL File]

1048021-78-8.mol
[Molecular Weight]

546.22
Chemical PropertiesBack Directory
[pka]

0.796±0.50(predicted)
Hazard InformationBack Directory
[Uses]

3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm-1, which determines the DNA sequences continuously[1].
[References]

[1] Palla M, et al., DNA sequencing by synthesis using 3'-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection. RSC Adv. 2014 Jan 1;4(90):49342-49346. DOI:10.1039/C4RA08398A
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