| Identification | Back Directory | [Name]
2-Propanol, 1-[[(2,4-difluorophenyl)methyl](phenylmethyl)amino]-3-(2-furanylmethoxy)- | [CAS]
1048244-34-3 | [Synonyms]
ANAT?inhibitor-2
ANATu00A0inhibitor-2
2-Propanol, 1-[[(2,4-difluorophenyl)methyl](phenylmethyl)amino]-3-(2-furanylmethoxy)- | [Molecular Formula]
C22H23F2NO3 | [MOL File]
1048244-34-3.mol | [Molecular Weight]
387.42 |
| Chemical Properties | Back Directory | [Boiling point ]
493.7±45.0 °C(Predicted) | [density ]
1.240±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
13.85±0.20(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
ANAT inhibitor-2 is a ANAT inhibitor for canavan disease, with an IC50 value of 20 μM. | [References]
[1] Ne?uta O, et al. High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan Disease. ACS Chem Neurosci. 2021 Sep 15;12(18):3445-3455. DOI:10.1021/acschemneuro.1c00455 |
|
|