| Identification | Back Directory | [Name]
(S)-7,8-Dihydro-3,6-dihydroxy-1,7,7,8-tetramethylacenaphtho[5,4-b]furan-4,5-dione | [CAS]
104855-19-8 | [Synonyms]
Sclerodione
(S)-7,8-Dihydro-3,6-dihydroxy-1,7,7,8-tetramethylacenaphtho[5,4-b]furan-4,5-dione | [MOL File]
104855-19-8.mol |
| Hazard Information | Back Directory | [Uses]
Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM)[1][2][3]. | [References]
[1] William A. et al. Metabolites produced by the Scleroderris canker fungus, Gremmeniellaabietina. Part 1. Canadian Journal of Chemistry. 1986. 64(8): 1585-1589.
[2] Hidayat Hussain, et al. Phytochemical investigation and antimicrobial activity of an endophytic fungus Phoma sp.Journal of King Saud University - Science. Volume 27, Issue 1, January 2015, Pages 92-95.
[3] Macabeo APG, et al. Alpha-Glucosidase- and Lipase-Inhibitory Phenalenones from a New Species of Pseudolophiostoma Originating from Thailand. Molecules. 2020 Feb 20;25(4):965. DOI:10.3390/molecules25040965 |
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