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104869-26-3

104869-26-3 Structure

104869-26-3 Structure
IdentificationBack Directory
[Name]

NF 157
[CAS]

104869-26-3
[Synonyms]

NF 157
8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt
[Molecular Formula]

C49H28F2N6O23S6.6Na
[MDL Number]

MFCD09038561
[MOL File]

104869-26-3.mol
[Molecular Weight]

1437.11
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Powder
[color ]

Off-white to pink
[Water Solubility ]

Soluble to 50 mM in water
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

NF 157 is an inhibitor of the P2Y11 receptor.
[Biological Activity]

Purinergic receptor antagonist that potently inhibits P2Y 11 receptor activity (IC 50 = 463 nM). Displays selectivity for P2Y 11 and P2X 1 receptors over P2Y 1 , P2Y 2 , P2X 2 , P2X 3 , P2X 4 and P2X 7 receptors. Inhibits NAD + -induced activation of human granulocytes.
[storage]

Desiccate at RT
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