ChemicalBook--->CAS DataBase List--->1049780-58-6

1049780-58-6

1049780-58-6 Structure

1049780-58-6 Structure
IdentificationBack Directory
[Name]

AUTEN-99
[CAS]

1049780-58-6
[Synonyms]

AUTEN-99
Auten-99 HBr
AUTEN-99 hydrobromide
AUTEN-99;AUTEN 99;AUTEN99
Auten-99 hydrochloride. Auten-99 HBr
2-(4-phenylphenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole
2-([1,1'-Biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide
2-([1,1'-Biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide
Autophagy enhancer99,Auten 99 HBr,Autophagy enhancer-99,inhibit,Autophagy enhancer 99,Auten99 HBr,Inhibitor
[Molecular Formula]

C17H15BrN2S
[MDL Number]

MFCD07281912
[MOL File]

1049780-58-6.mol
[Molecular Weight]

359.29
Chemical PropertiesBack Directory
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[solubility ]

DMSO: soluble
[form ]

A solid
Hazard InformationBack Directory
[Uses]

AUTEN-99 (hydrobromide) is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14). AUTEN-99 (hydrobromide) crosses the blood-brain barrier and exerts potent neuroprotective effects[1].
[References]

[1] Kovács T, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017 Feb 16;7:42014. DOI:10.1038/srep42014
Spectrum DetailBack Directory
[Spectrum Detail]

AUTEN-99(1049780-58-6)1HNMR
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